Click here to see publications by Dr. Thomas L. Rothstein, MD, PhD, in PubMed.

Griffin DO, Holodick NE, and Rothstein TL.  (2011) Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype, CD20+CD27+CD43+CD70-. J Exp Med. 208:67.

Rothstein TL.  (2011)  Grand challenges in B cell biology. Front B Cell Biol. 2:2.

Tumang JR, Holodick NE, Kaku H, and Rothstein TL.  (2011) A CD25-positive population of activated B1 cells expresses LIFR and responds to LIF. Front B Cell Biol., in press.

Zhong X and Rothstein TL. (2011) L2pB1: A new player in autoimmunity. Mol Immunol, in press.

Holodick NE, Tumang JR, and Rothstein TL. (2010) Immunoglobulin secretion by B1 cells: Differential intensity and IRF4-dependence of spontaneous IgM secretion by peritoneal and splenic B1 cells. Eur J Immunol. 40:3007.

Kaku H and Rothstein TL.  (2010) Octamer binding protein 2 (Oct2) regulates PD-L2 gene expression in B1 cells through lineage-specific activity of a unique intronic promoter.  Genes Immun. 11:55.

Kaku H and Rothstein TL.  (2009)  FAIM expression in B cells is regulated through IRF4 in a feed-foward fashion.  J Immunol. 183:5575.

Zhong X, Lau S, Bai C, Degauque N, Holodick NE, Steven SJ, Gao W, and Rothstein TL. (2009) A novel subpopulation of B1 B cells is enriched with autoreactivity in normal and lupus-prone mice.  Arthr Rheum. 60:3734.  

Holodick NE, Tumang JR, and Rothstein TL. (2009) Continual signaling is responsible for constitutive ERK phosphorylation in B-1 cells.  Mol Immunol. 46:3029.

Holodick N, Repetny K, Zhong X, and  Rothstein TL. (2009)  Adult bone marrow generates B1 cells containing abundant N-region additions. Eur J Immunol. 39:2383.

Kaku H and Rothstein TL.  (2009)  FAIM enhances CD40 signaling in B cells and augments the plasma cell compartment. J Immunol. 183:1667.
 
Repetny KJ, Zhong X, Rothstein TL, and Hansen UM. (2009)  Specific binding of LBP-1a to a subset of immunoglobulin switch regions in vivo corresponds to isotype-specific repression of class switch recombination.  Eur J Immunol., 39:1387.

Rothstein TL and Guo B. (2009)  B cell receptor crosstalk: Reprogramming BCR signaling to an alternate pathway results in expression and secretion of the autoimmunity-associated cytokine, osteopontin.  J Internal Med. 265:632.

Hemond MSC, Rothstein TL, and Wagner G.  (2009)  The C-terminal domain of Fas apoptosis inhibitory molecule (FAIM) is a novel fold.  J Mol Biol. 386:1024.

Guo B, Tumang JR, and Rothstein TL.  (2009)  B cell receptor crosstalk: B cells express osteopontin through the combined action of the alternate and classical BCR signaling pathways. Mol Immunol. 46:587.