The Litwin-Zucker Center for Research in Alzheimer's Disease and Memory Disorders is a large research and clinical program devoted to figuring out Alzheimer's disease at every level -- from basic biology to clinical response to medications. The Center supports almost two dozen Feinstein scientists who are running dozens of projects in the laboratory and with patients suffering from Alzheimer's and other age-related memory problems. There are studies looking for genes that put people at risk for Alzheimer’s, experimental drug trials, brain imaging, neurocognitive testing and basic research on the pathological hallmarks of Alzheimer’s – the plaques and tangles that are found in the brains of patients.
 
Patients and their families are part of longitudinal studies to test a wide range of factors in an attempt to identify subtle changes in behavior or mood that could be targeted with treatment. Scientists are conducting studies on cognitive aging in normal people and those with memory impairments. The goal of the Center is to figure out what causes Alzheimer’s and identify ways to detect and treat the debilitating disease. The Center has a number of clinical studies that test the benefits of current treatments over the course of the disease. In 2008, scientists in the Center have discovered a new risk gene for Alzheimer’s disease, a novel treatment that is heading into clinical trials and a new way of looking at the biological triggers for Alzheimer’s disease. Almost two dozen Feinstein scientists have made a commitment to study Alzheimer’s disease and they are coming at the mind-robbing disorder from every angle.
 
There are studies looking for genes that put people at risk for Alzheimer’s, experimental drug trials, brain imaging, neurocognitive testing and basic research on the pathological hallmarks of Alzheimer’s – the plaques and tangles that are found in the brains of patients. Patients and their families also come to the Center to be part of longitudinal studies to test a wide range of factors over time to identify subtle changes in behavior or mood that could be targeted with treatment.
 
Scientists are conducting studies on cognitive aging in normal people and those with memory impairments. The goal of the Center is to figure out what causes Alzheimer’s and identify ways to detect and treat the debilitating disease. The Center has a number of clinical studies that test the benefits of current treatments over the course of the disease.
 
In 2008, scientists in the Center have discovered a new risk gene for Alzheimer’s disease, a novel treatment that is heading into clinical trials and a new way of looking at the biological triggers for Alzheimer’s disease.

Center Labs:

Laboratory for Alzheimer's Disease Research - Peter Davies, PhD

Laboratory of Memory Disorders - Philippe Marambaud, PhD

Laboratory of Transcriptional Profiling - Concepcion Goldberg, PhD

Program for Alzheimer's Disease: Clinical Research  - Peter Davies, PhD

Administrative Staff:
 

		Name:  Erica Christen Position: Administrative Director Phone: (516) 487-3492 Email: echriste@nshs.edu
		Name:  Michelle Gong Position: Coordinator Phone: (718) 487-3492 Email: mgong@nshs.edu