Selected Publications
Click here to view publications by Dr. Edmund J MIller, PhD, in PubMed.
Bruchfeld A, Carrero JJ, Qureshi AR, Lindholm B, Barany P, Heimburger O, Hu M, Lin X, Stenvinkel P, Miller EJ. (2009) Elevated Serum Macrophage Migration Inhibitory Factor (MIF) Concentrations in Chronic Kidney Disease (CKD) Are Associated with Markers of Oxidative Stress and Endothelial Activation. Mol Med. 15:70.
Merchant S, Nadaraj S, Chowdhury D, Parnell VA, Sison C, Miller EJ, Ojamaa K. (2008) Macrophage migration inhibitory factor in pediatric patients undergoing surgery for congenital heart repair. Mol Med. 14:124.
Dhanantwari P, Nadaraj S, Kenessey A, Chowdhury D, Al-Abed Y, Miller EJ, Ojamaa K. (2008) Macrophage migration inhibitory factor induces cardiomyocyte apoptosis. Biochem Biophys Res Commun. 371:298.
Zaher TE, Miller EJ, Morrow DM, Javdan M, Mantell LL. (2007) Hyperoxia-induced signal transduction pathways in pulmonary epithelial cells. Free Radic Biol Med. 42:897.
Sakuragi T, Lin X, Metz CN, Ojamaa K, Kohn N, Al-Abed Y, Miller EJ. (2007) Lung-derived macrophage migration inhibitory factor in sepsis induces cardio-circulatory depression. Surg Infect (Larchmt). 8:29.
Pavlov V A, Ochani M, Yang LH, Gallowitsch-Puerta M, Ochani K, Lin X, Levi J, Parrish WR, Rosas-Ballina M, Czura CJ, Larosa GJ, Miller GJ, Tracey KJ, Al-Abed Y. (2007) Selective alpha7-nicotinic acetylcholine receptor agonist GTS-21 improves survival in murine endotoxemia and severe sepsis. Crit Care Med. 35:1139.
Morrow DM, Entezari-Zaher T, Romashko J, Azghani AO, Javdan M, Ulloa L, Miller EJ, Mantell LL. (2007) Antioxidants preserve macrophage phagocytosis of Pseudomonas aeruginosa during hyperoxia. Free Radic Biol Med. 42:1338.
Laragione T, Brenner M, Yarlett NC, Mello A, Miller EJ, Metz CN, Sherry B, Gulko PS. (2007) The arthritis severity quantitative trait locus Cia7 regulates neutrophil migration into inflammatory sites. Genes Immun. 8:147.
Laragione T, Yarlett NC, Brenner M, Mello A, Sherry B, Miller EJ, Metz CN, Gulko PS. (200). The arthritis severity quantitative trait loci Cia4 and Cia6 regulate neutrophil migration into inflammatory sites and levels of TNF-alpha and nitric oxide. J Immunol. 178:2344.
Gao L, Flores C, Fan-Ma S, Miller EJ, Moitra J, Moreno L, Wadgaonkar R, Simon B, Brower R, Sevransky J, Tuder RM, Maloney JP, Moss M, Shanholtz C, Yates CR, Meduri GU, Ye SQ, Barnes KC, Garcia JG. (2007) Macrophage migration inhibitory factor in acute lung injury: expression, biomarker, and associations. Transl Res. 150:18.
Dabideen DR, Cheng KF, Aljabari B, Miller EJ, Pavlov VA, Al-Abed Y. (2007) Phenolic hydrazones are potent inhibitors of macrophage migration inhibitory factor proinflammatory activity and survival improving agents in sepsis. J Med Chem. 50:1993.
Crichlow, G.V, Cheng KF, Dabideen D, Ochani M, Aljabari B, Pavlov VA, Miller EJ, Lolis E, Al-Abed Y. (2007) Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor. J Biol Chem. 282:23089.
Babu AN, Murakawa T, Thurman JM, Miller EJ, Henson PM, Zamora MR, Voelkel NF, Nicolls MR. (2007) Microvascular destruction identifies murine allografts that cannot be rescued from airway fibrosis. J Clin Invest. 117:3774.
Sakuragi T, Lin X, Metz CN, Ojamaa K, Kohn N, Al-Abed Y, Miller EJ. (2006) Lung-Derived Macrophage Migration Inhibitory Factor in Sepsis Induces Cardio-Circulatory Depression. Surgical Infection. [IN PRESS].
Hirayama S, Shiraishi T, Shirakusa T, Higuchi T, Miller EJ. (2006) Prevention of neutrophil migration ameliorates rat lung allograft rejection. Mol Med. 12:208.
Al-Abed Y, Dabideen D, Aljabari B, Valster A, Messmer D, Ochani M, Tanovic M, Ochani K, Bacher M, Nicoletti F, Metz CN, Pavlov VA, Miller EJ, Tracey KJ. (2005) ISO-1 binding to the tautomerase active site of MIF inhibits its pro-inflammatory activity and increases survival in severe sepsis. J. Biol. Chem. 280:36541.