Role of Topical Tranexamic Acid in Total Hip Arthroplasty (11-253B)

Protocol ID

11-253B

Protocol Description

Total hip replacement surgery is always associated with some blood loss. The purpose of this study is to see whether using tranexamic acid locally in the wound, in such procedures, will help reduce blood loss. Tranexamic acid is a drug which is known to affect the blood clotting system. It can help decrease blood loss. This drug has been commonly used to decrease blood loss in dental procedures, heart surgery procedures, and orthopedic procedures like hip and knee replacements. Tranexamic acid is a FDA approved drug. However, using tranexamic acid for total hip replacement is an off -label use which is not approved by the FDA. This study involves monitoring and recording blood loss by keeping a record of hemoglobin (protein that helps carry oxygen in the blood) levels. This study will also monitor the drug’s effects on recovery from surgery in the form of improvement in day to day functions after surgery.

Eligibility Criteria

  • Patients undergoing total hip replacement
  • Ages 18-80 years old

Primary Investigator(s)

  • Dr. Jose A. Rodriguez

Contact Information

Parthiv Rathod, MD
(212) 434-6256
prathod@nshs.edu

Last Update

January 20, 2012
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