2016 Scholarly activities of current students

Abstracts accepted/presented at local, national and international scientific meetings

Oral Presentations:

Bolognese AC, Sharma A, Yang WL, Nicastro JM, Coppa GF, Wang P. Cold-inducible RNA-binding protein promotes a Th1 T cell response via TLR4 in sepsis. February 2016. 11th Annual Academic Surgical Congress: Jacksonville, FL.

Bolognese AC, Yang WL, Hansen LW, Sharma A, Nicastro JM, Coppa GF, Wang P. Induction of invariant natural killer T (iNKT) cell anergy attenuates systemic and pulmonary inflammation in neonatal sepsis. October 2016. American College of Surgeons Clinical Congress: Washington, DC.

Maloney, C, Symons, S, Soffer, SZ, Steinberg BM. Potential use of neuronal stimulation to prevent surgery-induced acceleration of tumor metastasis. June 2016 The Feinstein Institute for Medical Research Scientific Retreat. Cold Spring Harbor NY.

Maloney, C, Symons, S, Soffer, SZ, Steinberg BM. Epidermal Growth Factor Receptor Inhibition Decreases Macrophage-Promoted Osteosarcoma Invasion. October 2016. American College of Surgeons Clinical Congress. Washington, DC.

Mughrabi, I . The Spleen in Focus: Optimizing the Effects of the Cholinergic Anti-inflammatory Pathway on Auto-inflammation for Direct Organ Stimulation. June 2016 The Feinstein Institute for Medical Research Scientific Retreat. Cold Spring NY.

Mughrabi, I. The Cholinergic Anti-inflammatory Pathway Controls Auto-inflammation in a Model of Familial Mediterranean Fever. April 2016 National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland.

Poster presentations

Bolognese, AC, Yang WL, Hansen LW, Sharma A, Nicastro JM, Coppa GF, Wang, P. Activation of hepatic invariant natural killer T cells exacerbates lung inflammation and apoptosis in neonatal sepsis. June 2016 39th Annual Conference on Shock: Austin, TX.

Bolognese AC, Yang WL, Wang Z, Nicastro JM, Coppa GF, Wang P. A novel inflammatory mediator causes lung injury in sepsis. May 2016 American Pediatric Surgical Association Annual Meeting: San Diego, CA.

Imperato GH, Hanes WM, Chavan SS, Tracey KJ. Neural Regulation of Antigen Trafficking through the Lymphatic System. June 2016, The Shock Society Annual Meeting, Austin, Texas

Imperato GH, Gunasekaran M, Tsaava T, Hanes WM, Chavan SS, Tracey KJ. A TRPV1-/NaV1.8+ Subset of Neurons Mediates Lymphatic Antigen Restriction. Accepted. Society for Neuroscience Annual Meeting November 2016

Lee, J.Y., Stevens T. Aerobic glycolysis is sufficient, but not necessary, for rapid proliferation of pulmonary endothelial cells. May 2016 International Conference of American Thoracic Society,

Maloney, C, Symons, S, Soffer, SZ, Steinberg BM. Colony stimulating factor-1 receptor (CSF-1R) and epidermal growth factor receptor (EGFR) Inhibition Decreases Macrophage-Promoted Invasion in Osteosarcoma.  October 2016 American Academy of Pediatric National meeting.

Maloney, C, Symons, S, Soffer, SZ, Steinberg BM. Epidermal Growth Factor Receptor Inhibition Decreases Macrophage-Promoted Osteosarcoma Invasion. Sohn Conference: Pediatric Cancer in a Post-genomic World. March 2016 The New York Academy of Sciences, New York, NY.

Maloney, C, Symons, S, Soffer, SZ, Steinberg BM. Epidermal Growth Factor Receptor Inhibition Decreases Macrophage-Promoted Osteosarcoma Invasion. June 2016 Northwell Academic Day.

Maloney, C, Symons, S, Soffer, SZ, Steinberg BM. Epidermal Growth Factor Receptor Inhibition Decreases Macrophage-Promoted Osteosarcoma Invasion. June 2016 The Feinstein Institute for Medical Research Scientific Retreat. Cold Spring NY.

Nazem A, Tang CC, Ma Y, Peng S, Spetsieris P, Dhawan V, Eidelberg D, Functional Brain Networks In Early Differential Diagnosis Of Dementia, June 2016 The 2016 Alzheimer’s Disease Congress, London, UK

Sankowski R, Huerta P, and Al-Abed Y. Endogenous Retrovirus-Driven Cognitive Impairment and Brain Inflammation, July 2016 10th Federation of European Neurosciences Societies Forum of Neuroscience, Copenhagen, Denmark.

Publications in peer-reviewed scientific journals

Bolognese AC, Sharma A, Yang WL, Nicastro JM, Coppa GF, Wang P. 2016. Cold-inducible RNA-binding protein activates splenic T cells during sepsis in a TLR4-dependent manner. Cell Mol Immunol. [In press].

Lee JY, Linge HM, Ochani K, Lin K, Miller EJ 2016 Regulation of angiopoietin-2 secretion from human pulmonary microvascular endothelial cells. Experimental lung research [In press].

Lee JY, Linge HM, Ochani K, Lin K, Miller EJ NSF inhibition prevents vascular instability following Gram positive pulmonary challenge. PLoS ONE 2016 Jun 29;11(6): e0157837

Mattis P, Niethammer M, Wataru S, Tang CC, Nazem A, Gordon M, Vicky B, Dhawan V, Eidelberg, D , Distinct Brain Networks Underlie Cognitive Dysfunction in Parkinson’s and Alzheimer’s Diseases, Neurology, [In press].

Tripathi M, Tang CC, Feigin A, De Lucia I, Nazem A, Dhawan V, Eidelberg D, Automated Differential Diagnosis of Early Parkinsonism Using Metabolic Brain Networks: A Validation Study.J Nucl Med. 2016 Jan;57(1):60-6. doi: 10.2967/jnumed.115.161992.

Awards

Caroline Maloney: First Place, Research Investigator Science Exposition, “Blocking the Spread of Childhood Bone Cancer”, Feinstein Institute for Medical Research.

Caroline Maloney: Second Place Poster Presentation Northwell Academic Day, “Epidermal Growth Factor Receptor Inhibition Decreases Macrophage-Promoted Osteosarcoma Invasion.” Feinstein Institute for Medical Research

Amir Nazem: Nominated for the Innovation Award (Northwell Heath 2016 President Award) forDementia vs Alzheimer’s”.