More than 20 million Americans may have kidney disease. Kidney disease occurs when the kidneys are no longer able to perform their function of removing waste and extra water from the blood because they are damaged. Kidney disease is most often caused by diabetes or high blood pressure. Acute kidney injury can occur following complications with pregnancy or a traumatic injury associated with blood loss, damage from severe infection, obstruction of urine flow, or damage from certain drugs or toxins.
Feinstein Institute researchers are conducting research to find more effective treatment for this disease, which includes ways to lessen the damage caused during acute kidney injury by reducing excessive inflammation that follows trauma.