Assistant Professor, The Litwin-Zucker Center for Alzheimer’s Disease & Memory Disorders,
The Feinstein Institute for Medical Research
Phone: (516) 562-3494
Dr. d’Abramo’s interest on Alzheimer’s disease started 15 years in the Laboratory of Experimental Medicine (Pathology) at the University of Genova. In those early years, the lab was focusing on aging cell biology and, collaborating with Dr. Massimo Tabaton, on the relationship between oxidative stress, activation of kinases (e.g. PKC) and the metabolism of APP.
During her PhD training at the University of Genova, Dr. d’Abramo had the privilege to join Dr. Peter Davies’ laboratory at the Albert Einstein College of Medicine as a visiting scientist, getting to learn more about the role of tau pathology in Alzheimer’s disease.
After defending her PhD thesis in Genova, Dr d’Abramo was offered a Postdoctoral position by Dr. Davies in the Alzheimer’s disease and Memory Disorder Center at the Feinstein Institute for Medical Research. First as a Postdoctoral trainee and later as an Institute Scientist, Cristina had the chance to gain considerable experience in working with models of tau pathology together with a continuous training in cell and molecular biology. Moreover, learning how to produce and handle tau monoclonal antibodies gave Dr. d’Abramo the opportunity to contribute to immunotherapy experiments and development of new tau assays, which turned into peer-reviewed publications.
Dr. d’Abramo has many open projects with different academic institutions and industry, and she maintains active collaboration with her parent institution in Genova as well.
The whole tau field has worked in the attempt to reduce tau phosphorylation and aggregation occurring in Alzheimer’s disease (AD). Dr. d’Abramo is currently studying the biology of tau protein in Alzheimer’s disease, its possible propagation between cells and the possibility of targeting aberrant tau with antibodies as a perspective treatment of Alzheimer’s.
Francesca Vitale, PharmD
The Feinstein Institute for Medical Research, Manhasset, NY
Field of Study: Alzheimer’s disease
University of Genova, Italy
Field of Study: Neurochemistry and Neurobiology
University of Genova, School of Medicine, Genova, Italy
Field of Study: Clinical Pathology
University of Genova, Genova, Italy
Field of Study: Biological Sciences
2017 National Institute on Aging, National Institute of Health R56 award, to test tau passive immunization using recombinant antibodies
2017 Innovation Award, Advancing Women in Science and Medicine, The Feinstein Institute for Medical Research, NY
2015 Declion Pharmaceuticals grant to test tau active immunization