Divyesh V. Sejpal, MD, MHCDS

Chief, Endoscopy, Division of Gastroenterology, Northwell Health

Professor of Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell

Phone: (516) 387-3990
Email: dsejpal@northwell.edu

About the Investigator
Dr. Sejpal is the Chief of Endoscopy, Division of Gastroenterology, for the Northwell Health System. He also serves as the Director of the Advanced Endoscopy Fellowship at North Shore University Hospital/Long Island Jewish Medical Center and as the Director of the Pancreaticobiliary Program at North Shore University Hospital. His clinical interests include advanced endoscopic imaging modalities, therapeutic endoscopy, and management of complex pancreaticobiliary diseases. He has introduced state-of-the-art technology, innovative techniques, and cutting-edge research to the enterprise.

Dr. Sejpal, a graduate of American University of the Caribbean medical school, completed his internal medicine residency and gastroenterology fellowship at the University of Virginia. He then completed an advanced endoscopy fellowship at Columbia University. Subsequently, he developed advanced endoscopy programs at Mount Sinai Medical Center in New York and at Baylor College of Medicine in Houston. He recently completed a Masters in Healthcare Delivery Science at Dartmouth College/ Tuck School of Business. Dr. Sejpal is Professor of Medicine at the Hofstra Northwell School of Medicine.

Research Focus
Dr. Sejpal has served as principal investigator and co-investigator on multiple funded clinical trials pertaining to advanced imaging modalities and therapeutic endoscopy. Recent trials include:

  • Prospective evaluation of cholangioscopy in the detection of residual biliary stones that are missed during ERCP
  • Prospective, multicenter clinical evaluation needle-based confocal laser endomicroscopy (nCLE) for cystic tumors of the pancreas
  • Prospective, multicenter registry to define and validate image interpretation of dominant strictures in primary sclerosing cholangitis with probe-based confocal laser endomicroscopy (pCLE)
  • High resolution optical imaging of esophageal tissue using the NvisionVLE™ imaging system registry
  • Evaluation of carbon dioxide insufflation for endoscopic procedures: a prospective observational study
  • Prospective study of the WallFlex Biliary RX fully covered stent for the treatment of anastomotic biliary strictures in post liver transplant patients

Dr. Sejpal’s research interests have also expanded to the Bioskills Education Center where he is investigating the utilization of cadaveric specimens for training of GI fellows and workshops for medical professionals and industry.

Education

Dartmouth College/ Tuck School of Business
Degree: MHCDS
2017
Field of Study: Health Care Delivery Science

Rice University Jones Graduate School of Business
Degree: Graduate Certificate
2013
Field of Study: Health Care Management

American University of the Caribbean
Degree: MD
1998
Field of Study: Medicine

University of North Carolina, Chapel Hill, NC
Degree: BS
1993
Field of Study: Biology

Publications
  1. Trindade AJ, Hirten R, Slattery E, Inamdar S, Sejpal DV. “Endoscopic ultrasound fine needle aspiration of solid lesions on clopidogrel may not be a high-risk procedure for bleeding: a case series.” Digestive Endoscopy 2016; 28(2):216-9.
  2. Inamdar S, Slattery E, Bhalla R, Sejpal DV, Trindade AJ. “Comparison of Adverse Events for Endoscopic Versus Percutaneous Biliary Drainage in the Management of Malignant Biliary Tract Obstruction in an Inpatient National Cohort.” JAMA Oncol 2016;2(1):112-7.
  3. Stein PH, Lee C, Trindade AJ, Sejpal DV. “Size does matter: endoscopic closure of a large gastrocutaneous fistula.” Gastrointest Endosc. 2016 May;83(5):1033-4
  4. Inamdar S, Sejpal DV, Ullah M, Trindade AJ. “Weekend vs. Weekday Admissions for Cholangitis Requiring an ERCP: Comparison of Outcomes in a National Cohort.” Am J Gastroenterol. 2016 Mar;111(3):405-10
  5. Thomas A, Vamadevan AS, Slattery E, Sejpal DV, Trindade AJ. “Performing forward- viewing endoscopy at time of pancreaticobiliary EUS and ERCP may detect additional upper gastrointestinal lesions.” Endosc Int Open. 2016 Feb;4(2):E193
  6. Inamdar S, Berzin TM, Berkowitz J, Sejpal DV, Sawhney MS, Chutanni R, Pleskow DK, Trindade AJ. “Decompensated cirrhosis may be a risk factor for adverse events in endoscopic retrograde cholangiopancreatography.” Liver Int. 2016 Oct;36(10):1457-63.
  7. Stein P, Brun A, Zaidi H, Sejpal DV, Trindade AJ. “Successful Treatment of a Persistent Esophageal Lichen Planus Stricture With a Fully Covered Metal Stent.” ACG Case Rep J. 2016 Jan 20;3(2):98-100.
  8. Trindade AJ, Hirten R, Sejpal DV. “Use of digital cholangioscopy in a dilated bile duct for detection of small symptomatic bile duct stones.” Gastrointest Endosc. 2016 Aug;84(2):372
  9. Trindade AJ, Rishi A, Stein PH, Sejpal DV. “Use of volumetric laser endomicroscopy in staging multifocal superficial squamous carcinoma of the esophagus.” Gastrointest Endosc. 2016 Aug;84(2):369
  10. Trindade AJ, George BJ, Berkowitz J, Sejpal DV, McKinley MJ. “Volumetric laser endomicroscopy can target neoplasia not detected by conventional endoscopic measures in long segment Barrett’s esophagus.” Endosc Int Open. 2016 Mar;4(3):E318-22
  11. Sharaiha RZ, Tyberg A, Khashab MA, Kumta NA, Karia K, Nieto J, Siddiqui UD, Waxman I, Joshi V, Benias PC, Darwin P, DiMaio CJ, Mulder CJ, Friedland S, Forcione DG, Sejpal DV, Gonda TA, Gress FG, Gaidhane M, Koons A, DeFilippis EM, Salgado S, Weaver KR, Poneros JM, Sethi A, Ho S, Kumbhari V, Singh VK, Tieu AH, Parra V, Likhitsup A, Womeldorph C, Casey B, Jonnalagadda SS, Desai AP, Carr-Locke DL, Kahaleh M, Siddiqui AA. “Endoscopic Therapy With Lumen-apposing Metal Stents Is Safe and Effective for Patients With Pancreatic Walled-off Necrosis.” Clin Gastroenterol Hepatol. 2016 May 14
  12. Trindade AJ, Thomas A, Sejpal DV, Inamdar S. “A modified EUS-guided rendezvous technique with needle-knife sphincterotomy over a transpapillary bile duct wire.” Gastrointest Endosc. 2016 Nov;84(5):862-863
  13. Trindade AJ, Sejpal DV, Sideridis K. “Digital pancreatoscopy in the management of main duct intraductal papillary mucinous neoplasm.” Gastrointest Endosc. Jul 2016.
  14. Trindade AJ, Passi M, Stein PH, Sejpal DV, Philip T. “Liquid nitrogen cryospray ablation in palliation of Barrett’s esophagus-associated adenocarcinoma.” Gastrointest Endosc. Jul 2016.
  15. Inamdar S, Han D, Passi M, Sejpal DV, Trindade AJ. “Rectal indomethacin is protective against post-ERCP pancreatitis in high-risk patients but not average-risk patients: a systematic review and meta-analysis.” Gastrointest Endosc. Sept 2016.

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