Colitis (in particular, ulcerative colitis which is limited to the colon) is the inflammation of the inner lining of the colon and can be associated with diarrhea, abdominal pain, bloating, and blood in the stool. In a model of experimental colitis, Feinstein researchers have shown that activation of the vagus nerve reduces these symptoms. Therapies involving the regulation of vagus nerve activity hold promise for the effective treatment of colitis.

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