Obesity and Metabolic Syndrome

Metabolic syndrome consists of a group of risk factors (increased blood pressure, a high blood sugar level, excess body fat around the waist and abnormal cholesterol levels) that increase the risk of heart disease. Chronic inflammation, as a result of immune and metabolic dysregulation, is observed in patients with obesity and metabolic syndrome. Feinstein Institute researchers have shown that dysregulation of vagus nerve-mediated anti-inflammatory signaling might contribute to the pathogenesis of obesity and its related comorbidities.

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