Bipolar disorder (also known as bipolar affective disorder, manic-depressive disorder, or manic depression) is a type of a mood disorder. Individuals with bipolar disorder experience episodes of very active behavior, known as mania, typically alternating with periods of depression. At the lower levels of mania, individuals appear energetic and excitable and may in fact be highly productive. At a higher level, individuals begin to behave erratically and impulsively, often making poor decisions due to unrealistic ideas about the future, and may have great difficulty with sleep. Individuals who experience manic episodes also commonly experience depressive episodes. Manic and depressive episodes typically last from a few days to several months and can be interspersed by periods of “normal” mood. Feinstein Institute researchers are making important contributions to early identification and treatment of adolescents and young adults who are at-risk for developing serious psychiatric illness, such as bipolar disorder, and are studying beneficial effects and side effects of antipsychotics medications.
Feinstein Institute investigators conducting bipolar disorder research include Barbara A. Cornblatt; Christoph U. Correll; Stephen L. Dewey; Betty Diamond; Vivian Kafantaris; John M. Kane; Todd Lencz; Ashesh Mehta and Delbert G. Robinson.