Philipp Homan, MD, PhD

Assistant Professor, The Center for Psychiatric Neuroscience, The Feinstein Institute for Medical Research

Phone: (718) 470-8267

About the Investigator

Dr. Homan is an assistant professor at the Center for Psychiatric Neuroscience at the Feinstein Institute for Medical Research. His research focus is the understanding of individual differences in response to treatment in psychotic and affective disorders. During his PhD in clinical neuroscience he has explored brain stimulation as a potential treatment for patients with chronic psychosis, and which factors might predict favorable outcomes. He has also applied brain stimulation in clinical settings in patients with depression and anxiety, and has taught courses in brain stimulation for medical doctors and graduate students.

Dr. Homan received his MD from Medical University Vienna, Austria. He completed his residency and an MD-PhD programme in Psychiatry at the University of Bern, Switzerland, where he also worked as an attending physician and as the group leader of the brain stimulation unit. A grant by the the Swiss National Science Foundation in 2015 allowed him to spend two years at Mount Sinai School of Medicine in New York with Daniela Schiller, PhD, an expert in the neural mechanisms of affective flexibility, after which he joined the faculty at the Feinstein Institute in August 2017.

Research Focus

Dr. Homan’s main interest is the understanding of individual differences in brain and behavior that may explain individual differences in response to treatment. He has used brain imaging to identify which patients might ultimately benefit from novel treatments such as brain stimulation that have less side effects than conventional pharmacological treatments. Along the same line, he has investigated differences in the brain’s reward system to predict which patients might ultimately suffer from substantial weight gain during pharmacological treatment, one of the most serious side effects of antipsychotic drugs.

Furthermore, he has studied differences in the learning behavior in patients exposed to combat trauma which may explain why some did develop posttraumatic stress disorder while others did not.

He is currently exploring the scope of individual response to treatment in patients with early-phase psychosis using statistical techniques and brain imaging.

Lab Members

Stephanie Winkelbeiner, Msc
Graduate Student and Research Coordinator
Phone: (718) 470-4588


Medical University, Vienna, Austria
Degree: MD
Field of Study: Medicine

University of Bern, Switzerland
Degree: PhD
Field of Study: Clinical neurosience

University of Bern, Switzerland
Field of Study: Psychiatry Residency

Icahn School of Medicine at Mount Sinai, NY
Degree: Postdoctoral fellowship in psychiatry

Honors and Awards

2018 Travel award from the Schizophrenia International Research Society
2016 Poster award from the Friedman Brain Institute at the 8th Annual Neuroscience Retreat
2015 Advanced Postdoc Mobility fellowship from the Swiss National Science Foundation
2014 Hans-Heimann-Preis from the Deutsche Gesellschaft fuer Psychiatrie, Psychotherapie und Nervenheilkunde
2014 Frutiger Award from the Foundation Adrian and Simone Frutiger
2011 Poster award from the DGPPN at the DGPPN Congress

    1. Homan P, Argyelan M, DeRosse P, Szeszko P, Gallego JA, Hanna L, Robinson DG, Kane JM, Lencz T, Malhotra AK (accepted). Structural similarity networks predict clinical outcome in early-phase psychosis. Neuropsychopharmacology.
    2. Homan P, Grob S, Milos G, Schnyder U, Eckert A, Lang U, Hasler G (2015a). The role of BDNF, leptin, and catecholamines in reward learning in bulimia nervosa. International Journal of Neuropsychopharmacology, 18(5).
    3. Homan P, Lin Q, Murrough JW, Soleimani L, Bach DR, Clem RL, Schiller D (2017b). Prazosin during threat discrimination boosts memory of the safe stimulus. Learning & Memory, 24(11): 597-601.
    4. Homan P, Ely BA, Yuan M, Brosch T, Ng J, Trope Y, Schiller D (2017a). Aversive smell associations shape social judgment. Neurobiology of Learning and Memory, 144: 86-95
    5. Homan P, Reddan MC, Brosch T, Koenigsberg HW, Schiller D (2017c). Aberrant link between empathy and social attribution style in borderline personality disorder. Journal of Psychiatric Research, 94: 163–171.
    6. Hu J, Wang W, Homan P, Wang P, Zheng X, Schiller D (2018). Reminder duration determines threat memory modifcation in humans. Scientific Reports, 8: 8848.
    7. Kindler J, Jann K, Homan P, Hauf M, Walther S, Strik W, Dierks T, Hubl D (2015). Static and dynamic characteristics of cerebral blood flow during the resting state in schizophrenia. Schizophrenia Bulletin, 41: 163-70.
    8. Winkelbeiner S, Cavelti M, Federspiel A, Dierks T, Strik W, Horn H, Homan P (In press). Decreased blood flow in the right insula and middle temporal gyrus predicts negative formal thought disorder in schizophrenia. Schizophrenia Research.
    9. Kunzelmann K, Grieder M, van Swam C, Homan P, Hubl D, Dierks T (In press). Am i hallucinating or is my fusiform cortex activated? Functional activation differences in schizophrenia patients with and without hallucinations. The European Journal of Psychiatry.
    10. Cavelti M, Winkelbeiner S, Federspiel A, Walther S, Stegmayer K, Giezendanner S, Laimboeck K, Strik W, Horn H, Homan P (In press). Formal thought disorder in schizophrenia and white matter abnormalities: A tract-based spatial statistics analysis. Psychiatry Research: Neuroimaging.
    11. Cavelti M, Kircher T, Nagels A, Strik W, Horn H, Homan P (In press). Neuroimaging of formal thought disorder in schizophrenia: A systematic review. Schizoprenia Research.
    12. Winkelbeiner S, Suker S, Bachofner H, Eisenhardt S, Steinau S, Walther S, Federspiel A, Dierks T, Strik W, Homan P (2018). Targeting obsessive-compulsive symptoms with rTMS and perfusion imaging. The American Journal of Psychiary, (175): 81-83.
    13. Winkelbeiner S, Leucht S, Kane JM, Homan P (2018). Often claimed, rarely tested: differences in individual drug response. PsyArxiv. doi: 10.31234/
    14. Homan P, Argyelan M, Fales CL, DeRosse P, Szeszko P, Robinson DG,Lencz T, Malhotra AK (2018a). Striatal volume and functional connectivity predict weight gain in early-phase psychosis. bioRxiv. doi: 10.1101/501825.
    15. Homan P, Levy I, Feltham E, Gordon C, Hu J, Li J, Pietrzak RH, Southwick S, Krystal JH, Harpaz-Rotem I, Schiller D (in press). Neural computations of threat in the aftermath of combat trauma. Nature Neuroscience.
    16. Cavelti M, Thompson K, Hulbert C, Betts J, Jackson H, Francey S, Homan P, Chanen A (In press). Auditory verbal hallucinations and other psychotic symptoms in youth with borderline personality disorder. Early Intervention Psychiatry.
    17. Homan P, Lau H, Levy I, Raio C, Bach D, Carmel D, Schiller D  (2018b). Affective flexibility without perceptual  awareness. bioRxiv. doi: 10.1101/505545.

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