Shock is a medical condition in which there is inadequate blood flow that compromises delivery of oxygen and nutrients to vital organs. This can occur following a serious injury or surgical procedure (hemorrhagic shock), major illness or severe infection (septic shock). If untreated, shock can cause permanent organ damage or death.

Feinstein Institute researchers are studying several forms of shock that include hemorrhagic and septic shock and shock caused by traumatic injuries. They are identifying novel therapeutic targets involved in these processes and developing better therapies to prevent progression of organ damage caused by shock.

Feinstein Institute investigators studying shock include Jared M. Huston, Christine Metz, Valentin A. PavlovJose Prince, Barbara Sherry, Kevin Tracey, Haichao Wang and Ping Wang.