Trauma is a serious and life-threatening physical injury. It can potentially lead to secondary complications such as shock, respiratory failure and death. After traumatic injury, the body responds both locally and throughout the entire body to protect vital organs and heal any damage. One of these responses is inflammation. Inflammation is necessary for maintaining good health – without inflammation, wounds and infections would never heal. However, persistent and constant inflammation can damage tissue and organs, and lead to diseases.

Feinstein Institute researchers are developing better therapies to prevent the consequences of excessive inflammation. They are also creating new devises to monitor the functions of the injured brain during surgery. These devices will help clinicians tailor their procedures based on any changes that happen in or to the brain during surgery.

Feinstein Institute investigators who study trauma include Ona E. Bloom; Daniel A. Grande; Jared M. HustonRaj K. NarayanJose M. Prince and Ping Wang.